St. Luke's First in Region to Provide Novel Treatment for Avoiding Lower-Extremity Amputations

BETHLEHEM, Pa., March 6, 2025 /PRNewswire/ -- St. Luke's University Health Network physicians are offering a new minimally invasive procedure that offers hope to persons facing likely amputation of a lower extremity due to a permanently blocked artery, called chronic limb-threatening ischemia (CLTI).

St. Luke's vascular surgeon Jared Feyko, DO, became the first physician in the region to treat a patient with the LimFlow minimally invasive system to improve the blood supply to a patient's lower extremity. In the hybrid OR at St. Luke's Bethlehem Campus, he created a novel blood supply to the patient's foot using a vein rather than an artery, since the patient's artery was completely blocked. This saved the patient from a major amputation.

Many persons experiencing a totally blocked blood supply to their leg eventually must undergo major lower extremity amputation. These advanced, limb-threatening plaques commonly form in patients with diabetes or chronic kidney disease, or those who are long-time smokers. CLTI can cause foot pain, prevent wounds from healing and may ultimately require amputation.

"In patients with CLTI, whose diseased or damaged artery cannot serve as the blood supply to the lower limb, LimFlow technology enables us to adapt a vein so it will serve as an artery," explained Dr. Feyko.

LimFlow, approved by the FDA in 2023, comprises balloon catheters, endoscopic instruments and covered stents, which are inserted in veins. Physicians use ultrasound imaging technology for visual guidance during this delicate procedure.

"The LimFlow treatment can benefit select 'no-option' patients in whom all other medical and surgical options to correct arterial blockages have been exhausted," said Dr. Feyko, who has performed this innovative procedure on a total of 14 patients, thus far.

Using the LimFlow system, Dr. Feyko rerouted blood flow around the patient's totally blocked tibial leg artery in the calf. He then channeled flow it through a tiny puncture from the artery into the adjacent tibial vein, which he had modified to serve as an artery and become the new blood supply to the patient's foot.

Since undergoing this procedure, the patient has less pain in his lower leg and foot, their chronically infected foot/leg wounds are healing and, most importantly, they have been able to avoid total amputation of the once-in-jeopardy limb.

"This procedure, and subsequent tissue/limb survival, were possible only because we have access to the last-chance LimFlow treatment," Dr. Feyko continued. He estimates that dozens of patients per year will be able to undergo LimFlow at St. Luke's because their tibial artery and vein are adaptable to this limb-saving treatment.

About St. Luke's

Founded in 1872, St. Luke's University Health Network is a fully integrated, regional, non-profit network of more than 19,000 employees providing services at 15 campuses and 350+ outpatient sites. With annual net revenue of more than $4 billion, the Network's service area includes 11 counties in Pennsylvania and New Jersey. Dedicated to advancing medical education, St. Luke's is the preeminent teaching hospital in central-eastern Pennsylvania.

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SOURCE St. Luke’s University Health Network, Inc.